Copyright 1997

By: Chris Van Deelen  chrisv@nucleus.com

     I found the information to write up these diseases on a very interesting
and Informative web site called 'Outbreak'.  This site has an active outbreak
listing, plus information regarding some of the deadliest disease's known to
mankind.  If it wasn't for this web page, I would not have been able to create
this dreaded nasty to be used with the disease system I wrote up for The
Morrow Project.
     If interested, the address for the web site is listed below:

     www.outbreak.org/cgi-unreg/dynaserve.exe/index.html

Yellow Fever
     An acute infectious disease that does not last very long, with a course
that varies from mild to fatal.

Yellow Fever
     SU-(E)-STR-2+1D4 Days-5-3 hours
     Weakness, pain, nausea, puerpera.

     Sudden onset of fever, headache, backache, weakness, nausea, vomiting.
Characteristic signs are pulse slowing as temperature rises (the reverse of
what usually happens with fevers), and albuminuria (blood in the urine),
progressing to hemorrhagic symptoms: epistaxis (nosebleed), bleeding from the
mouth, hematemesis (coffee-ground or black vomit due to blood in the stomach),
melena (black stool due to digested blood). Jaundice occurs - hence the name
Yellow Fever.
     The incubation period/onset of symptoms is 3-6 days.
     It is transmitted by mosquitoes
     An infected person transmit can transmit Yellow Fever to others shortly
before onset of symptoms.
     A patient infectious to others after onset of symptoms for 3-5 days.
     Antibiotics have no effect on yellow fever virus. Treatment is
supportive; replacement of lost blood, measures to reduce the fever and damage
to the liver.
     There is no cure, but 50-95% of patients survive anyway. There is an
excellent vaccine which is effective for life.
     Survivors are immune for life.
What is its rate of reproduction?
     Transcription (copying) of the RNA and production of the viral proteins
take only a few minutes (9-12 minutes in the case of Kunjin virus, which is
related to yellow fever virus). But full replication actually includes
assembly and maturation of the complete virus particle, which takes some
hours.
     What are the vectors for Yellow Fever?
Mosquitoes.

